Previous meetings of the CTP network
6th meeting of the CTP network in Huesca
The last (6th) meeting of this CTP network was held in Huesca, Spain, on October 9th, 2009, participating groups from the Universities of Bordeaux 1, Basque Country, Navarra, Zaragoza, Barcelona and Toulouse 3.
The results presented in this meeting have generated different articles that are being published in a special volume of the Journal of Physiology and Biochemistry. These papers show different aspects related to:
1) Experimental nutrition, performed on laboratory animals. Based on previous observations relative to conjugated polyunsaturated fatty acids, a novel member of this family, namely jacaric acid, has been added to the diet during weeks and its potential use as anti-obesity agent has been assessed in rats (Miranda et al.). In parallel, a study of how short photoperiod could influence lipogenesis and lipolysis and, thus, could be involved in loss of appetite and weight loss, has been performed in Siberian hamsters (Atgié et al). Additionally, novel and recently patented methods for extracting fructose from plant waste reprocessing (apples not suitable to be sold in fruit display) have led to the production of various carbohydrate preparations that have been tested. Their supplementation to standard diet of mice has resulted in beneficial effects regarding glucose handling and insulin resistance (Dray et al.);
2) Adipose tissue metabolism, in humans and animal models. The differential effects of high-fat and high-sucrose diets on the hyperplasia and hypertrophy of adipocytes in the subcutaneous and visceral depots have been studied in obese rats (Boqué et al.), while the metabolic effects of the adipokine visfatin were explored in human subcutaneous adipocytes, focusing on lipolysis and glucose transport activities (Wanecq et al.);
3) Genetic procedures in obesity and insulin resistance. Different genes related to these diseases have been studied, such as the specific lysophosphatidic acid receptor-1, whose invalidation alters food intake in mouse (Dusaulcy et al.), and the pro-inflammatory cytokine interleukin 6, whose -174G/C polymorphism has been repeatedly linked to weight gain, high mortality and celiac disease in man (Moleres et al.); a project focusing on the genes encoding for water and glycerol transporter has also been open to debate.
4) Clinical studies including epidemiological approaches. Healthy effects of dietary components, such as plant sterols, have been examined on cholesterol absorption and metabolism as well as on cardiovascular risk (Sanclemente et al.). A thorough study of fat distribution in obese children and adolescents, its measurement, and its relationship with the metabolic risk has also indicated that currently more than 27 % of this population is obese in Aragon (Revenga et al.). The effects of weight loss on different health aspects, such as iron metabolism and C-reactive protein concentration, have been followed on a period of 6 months and more in overweight subjects with familial combined hyperlipidemia (Mateo-Gallego et al.).
We sincerely acknowledge the support of CTP (www. ctp.org) and the valuable organization of this 6th meeting by I. Marques and T. Sanclemente.
6th meeting held in Huesca
a talk on lack of insulin-like effect of visfatin in human adipose tissue
6th meeting held in Huesca (2)
alteration of food intake in mice lacking LPA-1 receptors
News from the satellite symposium of the II Congress of FESNAD:
The poster presented by:
Josep Mercader, Almudena Lomba, Xavier Brenachot, Fermin I. Milagro, and Christian Carpéné INSERM, U858, Institut de Médecine Moléculaire de Rangueil, IFR 31, 31432 Toulouse, France and Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Pamplona, Spain
Financiado por la Comunidad de Trabajo de los Pirineos y el proyecto DIOmed (SUDOE).
y intitulado:
" Efecto del antidepresivo fenelzina sobre la adiposidad en ratas y sobre la respuesta lipolítica y lipogénica en adipocitos humanos y de roedores "
ha sido premiado como mejor poster en la X edicion del Simposium Nacional de Obesidad, en Reus, 1-2 Marzo 2010
Josep Mercader, Almudena Lomba, Xavier Brenachot, Fermin I. Milagro, and Christian Carpéné INSERM, U858, Institut de Médecine Moléculaire de Rangueil, IFR 31, 31432 Toulouse, France and Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Pamplona, Spain
Financiado por la Comunidad de Trabajo de los Pirineos y el proyecto DIOmed (SUDOE).
y intitulado:
" Efecto del antidepresivo fenelzina sobre la adiposidad en ratas y sobre la respuesta lipolítica y lipogénica en adipocitos humanos y de roedores "
ha sido premiado como mejor poster en la X edicion del Simposium Nacional de Obesidad, en Reus, 1-2 Marzo 2010
Picture from the first transnational meeting of the CTP mini-network on obesty and diabetes
Held in Agen, 2003.
